Photochemically induced thrombosis combined with chronic restraint stress for modeling post-stroke depression in mice
The PIT-CRS model provides a comprehensive and reproducible platform for studying PSD. By integrating both ischemic injury and chronic stress, this model captures the multifaceted nature of PSD and offers valuable insights into its pathophysiology. Future research using this model could pave the way for the development of targeted therapies for PSD.
Authors
- Feng Gao (ORCID: https://orcid.org/0000-0002-4969-5195)
- Qingchen Wang (ORCID: https://orcid.org/0000-0003-1708-5656)
- Zhengchun Wang (ORCID: https://orcid.org/0000-0002-5140-051X)
- Zhengzheng Wang (ORCID: https://orcid.org/0009-0004-5500-9368)
- Tumarisi Tuersunjiang
Institutions
- Ningbo University (CN)
- Ningbo University Affiliated Hospital (CN)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2025-02-28
- DOI
- https://doi.org/10.3389/fnins.2025.1547551
- Citations
- 1
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.84