Serum-derived exosomal microRNAs as biomarkers for postoperative delirium

This study highlights specific miRNAs as potential biomarkers for POD and suggests their involvement in the underlying mechanisms of cognitive decline following surgery. By enhancing diagnostic capabilities and identifying potential therapeutic targets, our findings could lead to more effective POD management strategies for elderly patients. Further research is recommended to validate these miRNAs and evaluate their clinical utility for predictive screening and therapeutic interventions.

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Publication Details

Journal
Frontiers in Neuroscience
Published
2025-02-28
DOI
https://doi.org/10.3389/fnins.2025.1525230
Citations
2
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
Field-Weighted Citation Impact
3.09
Controls
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article

Serum-derived exosomal microRNAs as biomarkers for postoperative delirium

Yujun Lin, Ying‐Jie Chen, Min Xu, Danfeng Wang et al.
2 citations
Frontiers in Neuroscience
Intensive Care Unit Cognitive Disorders
3.09
article

Serum-derived exosomal microRNAs as biomarkers for postoperative delirium

Yujun Lin, Ying‐Jie Chen, Min Xu, Danfeng Wang, Xiaochun Zheng
article en
2 citations

Abstract

This study highlights specific miRNAs as potential biomarkers for POD and suggests their involvement in the underlying mechanisms of cognitive decline following surgery. By enhancing diagnostic capabilities and identifying potential therapeutic targets, our findings could lead to more effective POD management strategies for elderly patients. Further research is recommended to validate these miRNAs and evaluate their clinical utility for predictive screening and therapeutic interventions.

Frontiers in NeuroscienceVol. 19
Fujian Provincial Hospital (CN), Fuzhou University (CN)
Good health and well-being
Openalex Percentile: Top 11%
Intensive Care Unit Cognitive Disorders
3.09
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