Impact of gut dysbiosis on coenzyme Q10 levels

This study investigates the relationship between intestinal dysbiosis and coenzyme Q10 deficiency in a group of 13 patients. The results indicated that all participants exhibited a coenzyme Q10 deficiency, associated with imbalances in intestinal microbiota, elevated fecal pH, and a highmicrobialload, particularly for pathogenicspeciessuch as Candida albicans. These changes suggeset that dysbiosis may affect the absorption and utilization of coenzyme Q10, reducing metabolic efficiency and promoting oxidative stress. The study highlights the critical role of a balanced microbiota in maintaining optimal coenzyme Q10 levels, essential for mitochondrial and antioxidant health. Conclusions recommend dietary and probiotic interventions to restore microbiotic balance, aiming to improve coenzyme Q10 absorption and support the body’s energy and immune functions. These findings underscore the importance of monitoring and optimizing intestinal health in managing coenzyme Q10 deficiencies.

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Publication Details

Journal
Studia Universitatis Moldaviae Seria Științe ale Naturii
Published
2024-12-01
DOI
https://doi.org/10.59295/sum6(176)2024_23
Primary Topic
Coenzyme Q10 studies and effects
Type
article
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article

Impact of gut dysbiosis on coenzyme Q10 levels

Septimiu Toader Voidăzan, Camelia Ratea, Adriana-Daniela Socianu
Studia Universitatis Moldaviae Seria Științe ale Naturii
Coenzyme Q10 studies and effects
article

Impact of gut dysbiosis on coenzyme Q10 levels

Septimiu Toader Voidăzan, Camelia Ratea, Adriana-Daniela Socianu
article en

Abstract

This study investigates the relationship between intestinal dysbiosis and coenzyme Q10 deficiency in a group of 13 patients. The results indicated that all participants exhibited a coenzyme Q10 deficiency, associated with imbalances in intestinal microbiota, elevated fecal pH, and a highmicrobialload, particularly for pathogenicspeciessuch as Candida albicans. These changes suggeset that dysbiosis may affect the absorption and utilization of coenzyme Q10, reducing metabolic efficiency and promoting oxidative stress. The study highlights the critical role of a balanced microbiota in maintaining optimal coenzyme Q10 levels, essential for mitochondrial and antioxidant health. Conclusions recommend dietary and probiotic interventions to restore microbiotic balance, aiming to improve coenzyme Q10 absorption and support the body’s energy and immune functions. These findings underscore the importance of monitoring and optimizing intestinal health in managing coenzyme Q10 deficiencies.

Studia Universitatis Moldaviae Seria Științe ale Naturii(6 (176))
Universitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș (RO)
Openalex Percentile: Top 78%
Coenzyme Q10 studies and effects
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