Evaluating oxidative stress targeting treatments in in vitro models of placental stress relevant to preeclampsia
Our 2D <i>in vitro</i> models recapitulate the response of the first trimester trophoblast cells to preeclampsia-like stresses, modelling inappropriate placental development, and demonstrate therapeutic potential of repurposed treatments.
Authors
- Matt D. Johansen (ORCID: https://orcid.org/0000-0001-5553-5270)
- Zoran Cakic
- Dinara Afrose
- Lana McClements (ORCID: https://orcid.org/0000-0002-4911-1014)
- Milan Stefanović (ORCID: https://orcid.org/0000-0003-4927-6983)
- Nataša Karadžov Orlić (ORCID: https://orcid.org/0000-0003-1093-2760)
- Željko Miković (ORCID: https://orcid.org/0000-0002-4247-3290)
- Philip M. Hansbro (ORCID: https://orcid.org/0000-0002-4741-3035)
- Valentina Nikolić (ORCID: https://orcid.org/0000-0001-7184-0670)
Institutions
- University of Technology Sydney (AU)
- University of Nis (RS)
- Centenary Institute (AU)
- University of Belgrade (RS)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-02-28
- DOI
- https://doi.org/10.3389/fcell.2025.1539496
- Citations
- 10
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 20.57
Funders
- National Heart Foundation of Australia