CD69 predicts prognosis through immune cell infiltration and decitabine treatment response in acute myeloid leukemia
The study established a correlation between the expression of ITGB7, SCD, CD69 and the OS in AML patients. SCD, ITGB7 and age were identified as key prognostic factors. The multifaceted role of CD69 in AML, encompassing its association with prognosis, immune cell infiltration, and response to chemotherapy, underscores its potential as a key player in the complex landscape of AML pathogenesis and treatment response.
Authors
- Jianfei Fu (ORCID: https://orcid.org/0000-0002-3036-1056)
- Hao Wu (ORCID: https://orcid.org/0000-0002-8903-4658)
- Silang Zhu
- Bing Li (ORCID: https://orcid.org/0000-0002-7896-7903)
- Jie Zhou (ORCID: https://orcid.org/0000-0002-6991-9766)
- Lixin Lv
- Aibin Liang
Institutions
- Tongji University (CN)
- Tongji Hospital (CN)
Publication Details
- Journal
- Translational Cancer Research
- Published
- 2025-02-01
- DOI
- https://doi.org/10.21037/tcr-24-1550
- Citations
- 1
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 1.77