Development and validation of a prognosis prediction model for overall survival in correlation between butyrate metabolism and gastric cancer prognosis: Mendelian randomization and transcriptomics analysis
We identified two butyrate metabolic prognostic genes, namely, structural maintenance of chromosome 2 and heat shock protein beta-1, as the prognostic markers for GC. Furthermore, MR indicated no causal association between the butyrate metabolic pathway and GC.
Authors
- Yan Huang (ORCID: https://orcid.org/0000-0001-5466-7714)
- Zilu Chen (ORCID: https://orcid.org/0000-0003-1341-2330)
- Kun Mei (ORCID: https://orcid.org/0000-0003-0450-2000)
- Fangyu Wang
- Renjun Gu (ORCID: https://orcid.org/0000-0002-3334-9124)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Soochow University (CN)
Publication Details
- Journal
- Translational Cancer Research
- Published
- 2025-02-01
- DOI
- https://doi.org/10.21037/tcr-24-677
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00