Identification of the CeRNA axis of circ_0000006/miR-483-5p/KDM2B in the progression of aortic aneurysm to aorta dissection
The study identified a novel circ_0000006/miR-483-5p/KDM2B axis dysregulated during AD progression. Targeting this axis, especially circ_0000006, could be a potential strategy to mitigate the transition from AA to AD by modulating VSMC phenotype and function.
Authors
- Xiong Tan
- Weitao Jin (ORCID: https://orcid.org/0000-0001-6825-5657)
- Kai Hu (ORCID: https://orcid.org/0000-0002-2777-9080)
- Yong Liu (ORCID: https://orcid.org/0009-0000-9566-9863)
- Liang Wang (ORCID: https://orcid.org/0000-0001-5339-7484)
- Yinglong Lai
- Chaohu Xiang
- Ming Hou
- Yangchen He
- Yu Yan
- Hao Wang (ORCID: https://orcid.org/0009-0008-4494-6793)
Institutions
- Affiliated Hospital of North Sichuan Medical College (CN)
Publication Details
- Journal
- BMC Cardiovascular Disorders
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1186/s12872-025-04598-8
- Citations
- 3
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- Department of Science and Technology of Sichuan Province