Androgen receptor expression distribution characteristics in young female breast cancer patients in China: a study of clinicopathological features
This study revealed that in young female breast cancer patients in China, AR-positive breast cancer was significantly associated with the high expression of HRs, increased P53 expression and reduced EGFR expression. The expression status of AR can serve as a biomarker to predict therapeutic responses but could also influence the classification of molecular subtypes and the selection of treatment strategies.
Authors
- Yao Zhou (ORCID: https://orcid.org/0000-0002-6527-9802)
- Dan Gong (ORCID: https://orcid.org/0000-0002-3645-7200)
- Jianhong Tu
- Adam Ofri (ORCID: https://orcid.org/0000-0003-4940-4674)
- Yuexia Chen
- Rainer J. Klement (ORCID: https://orcid.org/0000-0003-1401-4270)
- Wei Qu (ORCID: https://orcid.org/0009-0000-9662-750X)
- Xiyan Li (ORCID: https://orcid.org/0000-0003-1792-7358)
- Swarna Lakshmi Arumugam
Institutions
- The University of Sydney (AU)
- Leopoldina Krankenhaus Schweinfurt (DE)
- Mount Vernon Cancer Centre (GB)
- Third Hospital of Nanchang (CN)
Publication Details
- Journal
- Translational Cancer Research
- Published
- 2025-02-01
- DOI
- https://doi.org/10.21037/tcr-2025-147
- Primary Topic
- Estrogen and related hormone effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00