Portal homograft in pancreatic head cancer surgery: first experience

A clinical case of extended combined pancreatectomy with vein reconstruction using a portal homograft in a 54-year-old patient with locally advanced ductal adenocarcinoma of the head of the pancreas is presented. Following the patient’s surgery, no data were obtained to confirm vascular thrombosis, circulatory disturbances in the portal and superior mesenteric veins, or impaired blood supply to the liver. Mesenteric-portal venous reconstruction with a portal homograft did not result in any vascular reconstruction-related complications and allowed a R0 resection to be achieved. On the example of the given clinical case we demonstrated the possibility of performing extended combined resection in locally advanced pancreatic cancer with involvement of portal and superior mesenteric veins. The use of a portal vein homograft may be a promising alternative to current angioplasty methods (autoprostheses, synthetic prostheses, xenografts).

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Publication Details

Journal
P A Herzen Journal of Oncology
Published
2025-02-28
DOI
https://doi.org/10.17116/onkolog20251401142
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
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article

Portal homograft in pancreatic head cancer surgery: first experience

A.V. Zavaruev, Roman Nikolaevich Komarov, I.O. Shchekoturov, M. Shao et al.
P A Herzen Journal of Oncology
Pancreatic and Hepatic Oncology Research
article

Portal homograft in pancreatic head cancer surgery: first experience

A.V. Zavaruev, Roman Nikolaevich Komarov, I.O. Shchekoturov, M. Shao, S S Novikov, S V Osminin
article en

Abstract

A clinical case of extended combined pancreatectomy with vein reconstruction using a portal homograft in a 54-year-old patient with locally advanced ductal adenocarcinoma of the head of the pancreas is presented. Following the patient’s surgery, no data were obtained to confirm vascular thrombosis, circulatory disturbances in the portal and superior mesenteric veins, or impaired blood supply to the liver. Mesenteric-portal venous reconstruction with a portal homograft did not result in any vascular reconstruction-related complications and allowed a R0 resection to be achieved. On the example of the given clinical case we demonstrated the possibility of performing extended combined resection in locally advanced pancreatic cancer with involvement of portal and superior mesenteric veins. The use of a portal vein homograft may be a promising alternative to current angioplasty methods (autoprostheses, synthetic prostheses, xenografts).

P A Herzen Journal of OncologyVol. 14(1)
Sechenov University (RU), Amur State Medical Academy (RU)
Openalex Percentile: Top 95%
Pancreatic and Hepatic Oncology Research
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