Reduction of subclinical acute cardiac injury through DIBH radiotherapy: a single-institution real-world clinical cohort analysis

The implementation of DIBH has been demonstrated to reduce the proportion of patients experiencing subclinical acute cardiac injury, with a higher proportion of patients returning to normalcy after one year. This finding suggests the potential reversibility of radiation-induced cardiac injury. The monitoring of these early cardiac biomarker changes to identify high-risk patients, followed by the implementation of early interventions, may contribute to a reduction in the incidence of long-term cardiac complications. Future research could integrate cardiac biomarkers, EKG, as well as traditional dosimetric parameters and baseline cardiac risk factors, to construct a more precise, individualized cardiac risk prediction model, thereby better assessing the long-term cardiac risks in patients.