Novel therapeutic strategy: Nrf2 activation in targeting senescence-related changes in chronic obstructive pulmonary disease
The findings underscore the potential of Nrf2 activation as a therapeutic strategy to mitigate COPD progression by modulating the senescence-associated secretory phenotype (SASP). This study suggests that Nrf2 activators could offer a promising approach to improving clinical outcomes for COPD patients.
Authors
- Shufang Pan
- Hui Lin (ORCID: https://orcid.org/0000-0001-7872-9924)
- Fan Jin (ORCID: https://orcid.org/0000-0002-5185-5231)
Institutions
- Wenzhou Medical University (CN)
Publication Details
- Journal
- Journal of Thoracic Disease
- Published
- 2025-02-01
- DOI
- https://doi.org/10.21037/jtd-24-710
- Citations
- 3
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 4.56