Efficacy and safety of integrating consolidative thoracic radiotherapy with immunochemotherapy in extensive-stage small cell lung cancer: a real-world retrospective analysis

The combination of cTRT with immunochemotherapy for ES-SCLC showed improved rwPFS and OS, indicating potential benefit in this population. The overall safety profile remained manageable. These findings highlight the need for further prospective studies to confirm the optimal integration of cTRT in ES-SCLC treatment strategies.

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Publication Details

Journal
Journal of Thoracic Disease
Published
2025-02-01
DOI
https://doi.org/10.21037/jtd-24-1592
Primary Topic
Lung Cancer Research Studies
Type
article
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article

Efficacy and safety of integrating consolidative thoracic radiotherapy with immunochemotherapy in extensive-stage small cell lung cancer: a real-world retrospective analysis

Hongfu Sun, Qian Wang, Minghui Wang, Xiaomeng Liu et al.
Journal of Thoracic Disease
Lung Cancer Research Studies
article

Efficacy and safety of integrating consolidative thoracic radiotherapy with immunochemotherapy in extensive-stage small cell lung cancer: a real-world retrospective analysis

Hongfu Sun, Qian Wang, Minghui Wang, Xiaomeng Liu, Qi Zhang, Dan Han, Chengwei Zhao, Chengxin Liu
article en

Abstract

The combination of cTRT with immunochemotherapy for ES-SCLC showed improved rwPFS and OS, indicating potential benefit in this population. The overall safety profile remained manageable. These findings highlight the need for further prospective studies to confirm the optimal integration of cTRT in ES-SCLC treatment strategies.

Journal of Thoracic DiseaseVol. 17(2)
Shandong University of Aeronautics (CN), Shandong Tumor Hospital (CN), Shandong First Medical University (CN), Lanzhou University (CN)
Good health and well-being
Openalex Percentile: Top 95%
Lung Cancer Research Studies
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