Admixture as a source for HLA variation in Neolithic European farming communities
Both early farmers and late farmers exhibit a relatively narrow HLA allele spectrum compared to today. This coincides with sparse traces of pathogen DNA, potentially indicating a lower pathogen pressure at the time.
Authors
- Joachim Pechtl (ORCID: https://orcid.org/0000-0002-3478-9084)
- Carola Berszin
- Michael Francken (ORCID: https://orcid.org/0000-0001-6336-2111)
- Gisela Grupe (ORCID: https://orcid.org/0000-0002-2731-2296)
- Nicolas Antonio da Silva (ORCID: https://orcid.org/0000-0002-1537-3286)
- Onur Özer (ORCID: https://orcid.org/0000-0003-2284-6181)
- Almut Nebel
- Kerstin Schierhold (ORCID: https://orcid.org/0000-0002-6136-6087)
- Magdalena Haller-Caskie (ORCID: https://orcid.org/0000-0003-3677-1504)
- Irina Görner
- Joachim Wahl (ORCID: https://orcid.org/0000-0002-5733-8905)
- Christoph Rinne (ORCID: https://orcid.org/0000-0002-9829-6182)
- Yan-Rong Chen (ORCID: https://orcid.org/0009-0007-0412-2741)
- Daniel Kolbe (ORCID: https://orcid.org/0000-0002-6607-7591)
- Ben Krause‐Kyora (ORCID: https://orcid.org/0000-0001-9435-2872)
- Sabine Schade-Lindig
- Johannes Müller (ORCID: https://orcid.org/0000-0002-3538-197X)
- Tobias L. Lenz (ORCID: https://orcid.org/0000-0002-7203-0044)
Institutions
- Universität Hamburg (DE)
- Universität Innsbruck (AT)
- Regierungspräsidium Stuttgart (DE)
- Christian-Albrechts-Universität zu Kiel (DE)
- Landesamt für Denkmalpflege Hessen (DE)
- Landschaftsverband Westfalen-Lippe (DE)
- Clinical Research Center Kiel (DE)
- University of Tübingen (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Genome biology
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1186/s13059-025-03509-6
- Citations
- 4
- Primary Topic
- T-cell and B-cell Immunology
- Type
- article
- Field-Weighted Citation Impact
- 3.19
Funders
- Deutsche Forschungsgemeinschaft