Protofibril packing density of individual fibers alters fibrinolysis
The present work highlights the crucial role that protofibril packing density plays in fibrinolysis. Our results suggest a need to consider the effect a disease has on protofibril packing density to inform about clot resistance and the development for more personalized lytic agents.
Authors
- Bradley Paynter (ORCID: https://orcid.org/0009-0002-6009-8225)
- Brittany E. Bannish (ORCID: https://orcid.org/0000-0003-0487-1041)
- Rebecca A Risman (ORCID: https://orcid.org/0009-0009-4915-9139)
- Valerie J. Tutwiler (ORCID: https://orcid.org/0000-0003-1213-4447)
- Victoria Percoco (ORCID: https://orcid.org/0009-0007-2656-2174)
Institutions
- Rutgers, The State University of New Jersey (US)
- University of Central Oklahoma (US)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1016/j.rpth.2025.102708
- Citations
- 1
- Primary Topic
- Diabetic Foot Ulcer Assessment and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.29
Funders
- National Science Foundation
- New Jersey Health Foundation
- New Jersey Commission on Spinal Cord Research
- National Institutes of Health
- Division of Civil, Mechanical and Manufacturing Innovation