Preoperative edema severity affects outcomes after Descemet membrane endothelial keratoplasty for Fuchs endothelial corneal dystrophy: a cohort study

DMEK for FECD yielded better visual acuity after 4 months when performed in the early stage of FECD compared to a later stage with clinical edema. This may be attributable to persistent corneal fibrosis after DMEK in eyes with preoperative clinically evident corneal edema, as suggested by higher postoperative corneal density in eyes with clinical edema. Consequently, the findings advocate for the consideration of earlier DMEK in FECD patients to achieve better surgical recovery.

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Publication Details

Journal
Eye and Vision
Published
2025-03-01
DOI
https://doi.org/10.1186/s40662-025-00425-5
Citations
5
Primary Topic
Corneal surgery and disorders
Type
article
Field-Weighted Citation Impact
6.80

Funders

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article

Preoperative edema severity affects outcomes after Descemet membrane endothelial keratoplasty for Fuchs endothelial corneal dystrophy: a cohort study

Hyeck-Soo Son, Lizaveta Chychko, Maximilian Hammer, Maximilian Friedrich et al.
5 citations
Eye and Vision
Corneal surgery and disorders
6.80
article

Preoperative edema severity affects outcomes after Descemet membrane endothelial keratoplasty for Fuchs endothelial corneal dystrophy: a cohort study

Hyeck-Soo Son, Lizaveta Chychko, Maximilian Hammer, Maximilian Friedrich, John T. Lind, Gerd Uwe Auffarth, Victor Aristide Augustin, Timur M. Yildirim
article en
5 citations

Abstract

DMEK for FECD yielded better visual acuity after 4 months when performed in the early stage of FECD compared to a later stage with clinical edema. This may be attributable to persistent corneal fibrosis after DMEK in eyes with preoperative clinically evident corneal edema, as suggested by higher postoperative corneal density in eyes with clinical edema. Consequently, the findings advocate for the consideration of earlier DMEK in FECD patients to achieve better surgical recovery.

Eye and VisionVol. 12(1)
Heidelberg University (DE), Augenklinik Heidelberg (DE)
Klaus Tschira Stiftung
Good health and well-being
Openalex Percentile: Top 3%
Corneal surgery and disorders
6.80
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