Clinicopathological Features of Diffuse Hemispheric Glioma, H3G34-Mutant

H3 G34 DHG occurs more significantly in younger patients, and nearly all lesions are located in the cerebral hemisphere. MRI showed mass effects, edema and mild enhancement. The histological type showed glioblastoma structure and PNET morphology. Immunohistochemistry showed that the expression of H3G34R was more significant in PNET morphology.

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Publication Details

Journal
Fetal and Pediatric Pathology
Published
2025-02-28
DOI
https://doi.org/10.1080/15513815.2025.2460560
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Clinicopathological Features of Diffuse Hemispheric Glioma, H3G34-Mutant

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Clinicopathological Features of Diffuse Hemispheric Glioma, H3G34-Mutant

Juan Cao, Guocheng Yang, Yongxian Chen, Hailun Chen, Jiaxin Liao, Zhijun Luo, Weiguo Cao, Xiaoxiao He, Zhihui Huang
article en

Abstract

H3 G34 DHG occurs more significantly in younger patients, and nearly all lesions are located in the cerebral hemisphere. MRI showed mass effects, edema and mild enhancement. The histological type showed glioblastoma structure and PNET morphology. Immunohistochemistry showed that the expression of H3G34R was more significant in PNET morphology.

Fetal and Pediatric PathologyVol. 44(2)
Shenzhen Children's Hospital (CN)
Zero hunger
Openalex Percentile: Top 94%
Glioma Diagnosis and Treatment
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