Regulation of cerebrovascular resistance below the lower limit of cerebral autoregulation during induced hypotension: an observational study
The continuing decline of CVR below the LLCA indicated that brain vasculature is still able to react on changing BP. This implies that LLCA should not be regarded as a fixed point but rather a transitional zone between exhausted and normally functioning autoregulation.
Authors
- David R. Koolbergen (ORCID: https://orcid.org/0000-0002-1297-5716)
- Eline Kho (ORCID: https://orcid.org/0000-0003-2001-4111)
- Rokus E.C. van den Dool (ORCID: https://orcid.org/0000-0002-5305-0621)
- Rogier V. Immink (ORCID: https://orcid.org/0000-0003-2427-6514)
- Denise Petra Veelo (ORCID: https://orcid.org/0000-0001-6196-1671)
- Alexander P. J. Vlaar (ORCID: https://orcid.org/0000-0002-3453-7186)
- Oskar T. Corsmit
- Nicolaas H. Sperna Weiland (ORCID: https://orcid.org/0000-0003-1305-1846)
- Sandjiv S. Mahes
Institutions
- Amsterdam Neuroscience (NL)
- Amsterdam University Medical Centers (NL)
- Amsterdam University of Applied Sciences (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- British Journal of Anaesthesia
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1016/j.bja.2024.12.037
- Citations
- 1
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 1.39