Characterization and chemoproteomic profiling of protein O-GlcNAcylation in SOD1-G93A mouse model
These data provide a valuable resource for dissecting the functional role of O-GlcNAcylation in ALS and shed light on promising therapeutic avenues for ALS. The chemoenzymatic labeling-based chemoproteomic approach is applicable for probing O-GlcNAc dynamics in various pathological processes.
Authors
- Zhongzhong Li (ORCID: https://orcid.org/0000-0003-0570-3197)
- Qingsong Xie (ORCID: https://orcid.org/0000-0001-6974-2019)
- Shaoyuan Lei
- Dongxiao Li (ORCID: https://orcid.org/0000-0001-9195-7753)
- Xinyan Du
- Yansu Guo (ORCID: https://orcid.org/0000-0002-4367-5353)
- Yi Hao (ORCID: https://orcid.org/0000-0002-7637-4282)
Institutions
- Hebei Medical University (CN)
- Shandong University (CN)
- Capital Medical University (CN)
- Beijing Geriatric Hospital (CN)
- First Affiliated Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1186/s10020-025-01134-4
- Citations
- 5
- Primary Topic
- Carbohydrate Chemistry and Synthesis
- Type
- article
- Field-Weighted Citation Impact
- 3.74
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province