Short- and long-term comparative effectiveness of nirmatrelvir/ritonavir and molnupiravir in asthma patients: a cohort study
Compared with molnupiravir, nirmatrelvir/ritonavir may offer more benefits in reducing the risk of post-acute sequelae of COVID-19 among asthma patients. In addition, the post-acute benefits of the antivirals were also demonstrated in patients with mild asthma, which have not been generally recommended in existing clinical management guidelines.
Authors
- Kehang Li (ORCID: https://orcid.org/0000-0002-3778-7068)
- Aimin Yang (ORCID: https://orcid.org/0000-0003-2968-1762)
- Zihao Guo (ORCID: https://orcid.org/0000-0001-9002-0483)
- Huwen Wang (ORCID: https://orcid.org/0000-0001-7443-9735)
- Tsz Yu Chow (ORCID: https://orcid.org/0000-0002-1295-6646)
- Renee W. Y. Chan (ORCID: https://orcid.org/0000-0001-6485-0926)
- Xiaoting Jiang (ORCID: https://orcid.org/0000-0002-4798-4508)
- Ka Chun Chong (ORCID: https://orcid.org/0000-0001-5610-1298)
- Kate Ching Ching Chan (ORCID: https://orcid.org/0000-0001-7272-8285)
- Eng‐Kiong Yeoh (ORCID: https://orcid.org/0000-0002-1721-9450)
- Chris Ka Pun Mok (ORCID: https://orcid.org/0000-0002-0525-6772)
- Conglu Li (ORCID: https://orcid.org/0000-0002-6210-6631)
- Carrie Ho Kwan Yam (ORCID: https://orcid.org/0000-0001-8353-9711)
- Chi Tim Hung (ORCID: https://orcid.org/0000-0003-2103-8377)
- David S.C. Hui (ORCID: https://orcid.org/0000-0003-4382-2445)
- Yawen Wang (ORCID: https://orcid.org/0000-0001-8763-9912)
- Yuchen Wei (ORCID: https://orcid.org/0000-0002-6817-9364)
- Guozhang Lin (ORCID: https://orcid.org/0009-0006-5996-2927)
- Shi Zhao
Institutions
- Chinese University of Hong Kong (HK)
- Prince of Wales Hospital (CN)
- Tianjin Medical University (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- Respiratory Research
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1186/s12931-025-03156-2
- Citations
- 1
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- Chinese University of Hong Kong
- Hong Kong Government
- Health and Medical Research Fund