Comprehensive evaluation of diabetes subtypes in a European cohort reveals stronger differences of lifestyle, education and psychosocial parameters compared to metabolic or inflammatory factors
The study validates the ANDIS classification framework's applicability not only at the time point of manifestation but also in cohorts with pre-existing diabetes. While we did not find major differences regarding the classical metabolic, microbial and nutritional parameters, we identified several significant associations with lifestyle factors. Our findings underscore the importance of personalized, subtype-specific therapies not solely focusing on anthropometric and laboratory markers but comprehensively addressing the patient's own personality and situation of life.
Authors
- Corinna Bang (ORCID: https://orcid.org/0000-0001-6814-6151)
- Julia Koppenhagen
- Kristina Schlicht (ORCID: https://orcid.org/0000-0003-0281-5142)
- Johannes Epe
- Dominik M. Schulte (ORCID: https://orcid.org/0000-0002-4622-6051)
- Katharina Hartmann
- Tanja C. Adam (ORCID: https://orcid.org/0000-0002-7840-5003)
- Nathalie Rohmann (ORCID: https://orcid.org/0000-0001-9038-5845)
- Corinna Geisler (ORCID: https://orcid.org/0000-0002-2383-3596)
- Matthias Laudes (ORCID: https://orcid.org/0000-0002-7846-955X)
- Tim Hollstein (ORCID: https://orcid.org/0000-0002-4048-2978)
- Andre Franke
- Kathrin Türk
- Lucy Kruse
- Ahmad Yusuf Kohestani
Institutions
- Christian-Albrechts-Universität zu Kiel (DE)
- Maastricht University (NL)
- Clinical Research Center Kiel (DE)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1186/s12933-025-02660-5
- Citations
- 6
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 4.84