Prospective planning comparison of magnetic resonance-guided vs. internal target volume-based stereotactic body radiotherapy of hepatic metastases – Which patients do really benefit from an MR-linac?
Dosimetrically, gated MRgRT was beneficial for virtually all the hepatic metastases analyzed in this study. Patients with metastases located critically near gastrointestinal OAR or with limited healthy liver volume should be allocated to centers providing MRgRT.
Authors
- Oliver Sedlaczek (ORCID: https://orcid.org/0000-0002-8709-5481)
- Heinz‐Peter Schlemmer (ORCID: https://orcid.org/0000-0002-9291-0954)
- C. Katharina Renkamp
- Sebastian Regnery (ORCID: https://orcid.org/0000-0002-6820-884X)
- Jakob Liermann (ORCID: https://orcid.org/0000-0002-1445-1940)
- Harold Lau (ORCID: https://orcid.org/0000-0003-0947-933X)
- Carolin Buchele
- Eva Meixner (ORCID: https://orcid.org/0000-0001-7087-9581)
- Line Hoeltgen (ORCID: https://orcid.org/0000-0002-3433-2455)
- Fabian Schlüter
- Laila König (ORCID: https://orcid.org/0000-0001-8402-6694)
- Kevin S. Zhang (ORCID: https://orcid.org/0000-0002-3611-5550)
- Sebastian Klüter (ORCID: https://orcid.org/0000-0003-3139-3444)
- Elisabetta Sandrini
- Nina I. Niebuhr (ORCID: https://orcid.org/0000-0002-5749-9645)
- Juliane Hörner‐Rieber (ORCID: https://orcid.org/0000-0003-3911-4438)
- Jürgen Debus (ORCID: https://orcid.org/0000-0002-6411-4811)
- Fabian Weykamp (ORCID: https://orcid.org/0000-0003-1731-7090)
- Philipp Hoegen-Saßmannshausen
- David Neugebauer
Institutions
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Düsseldorf University Hospital (DE)
- Heidelberger Institut für Radioonkologie (DE)
- National Center for Tumor Diseases (DE)
- Klinikum Ludwigsburg (DE)
- Deutsches Konsortium für Translationale Krebsforschung (DE)
- Heinrich Heine University Düsseldorf (DE)
Publication Details
- Journal
- Clinical and Translational Radiation Oncology
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1016/j.ctro.2025.100941
- Citations
- 2
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 3.77
Funders
- Pfizer
- AstraZeneca
- Sanofi
- Varian Medical Systems
- Novocure
- Accuray
- ViewRay
- Deutsche Forschungsgemeinschaft
- Dietmar Hopp Stiftung