IL-5 enhances human mast cell survival and interferon responses to viral infection
IL-5 signaling selectively promotes interferon responses in mast cells and maintains mast cell populations during mucosal viral infection via a novel IL-5/EPAS1 axis.
Authors
- Ian D. Haidl (ORCID: https://orcid.org/0000-0002-5301-0822)
- Christopher R. Liwski
- Jasmine Barra (ORCID: https://orcid.org/0000-0002-2400-1257)
- Tobias K. Karakach (ORCID: https://orcid.org/0000-0003-2460-3781)
- Daniel Gaston (ORCID: https://orcid.org/0000-0003-2841-8057)
- Liliana Portales‐Cervantes
- Jean S. Marshall (ORCID: https://orcid.org/0000-0002-5642-1379)
- Phoebe Phonchareon
Institutions
- Dalhousie University (CA)
- Nova Scotia Health Authority (CA)
- Beatrice Hunter Cancer Research Institute (CA)
Publication Details
- Journal
- Journal of Allergy and Clinical Immunology
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1016/j.jaci.2025.02.025
- Citations
- 7
- Primary Topic
- Mast cells and histamine
- Type
- article
- Field-Weighted Citation Impact
- 5.58