Improving Accuracy and Source Transparency in Responses to Soft Tissue Sarcoma Queries Using GPT-4o Enhanced with German Evidence-Based Guidelines

The RAG approach significantly enhanced the performance of GPT-4o in answering STS-related questions. However, the model still produced incorrect responses in certain complex scenarios. GPT-4o, even with RAG, should be used cautiously in clinical settings, particularly for rare diseases like sarcoma. Human expertise remains irreplaceable in medical decision-making.

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Publication Details

Journal
Oncology Research and Treatment
Published
2025-02-28
DOI
https://doi.org/10.1159/000544978
Citations
3
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
4.56
Controls
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article

Improving Accuracy and Source Transparency in Responses to Soft Tissue Sarcoma Queries Using GPT-4o Enhanced with German Evidence-Based Guidelines

Franka Menge, Cui Yang, Christoph Reißfelder, Peter Hohenberger et al.
3 citations
Oncology Research and Treatment
Sarcoma Diagnosis and Treatment
4.56
article

Improving Accuracy and Source Transparency in Responses to Soft Tissue Sarcoma Queries Using GPT-4o Enhanced with German Evidence-Based Guidelines

Franka Menge, Cui Yang, Christoph Reißfelder, Peter Hohenberger, Weiwei Jia, Jens Jakob, Chengpeng Li, Yanjun Chu, Tobias Speer
article en
3 citations

Abstract

The RAG approach significantly enhanced the performance of GPT-4o in answering STS-related questions. However, the model still produced incorrect responses in certain complex scenarios. GPT-4o, even with RAG, should be used cautiously in clinical settings, particularly for rare diseases like sarcoma. Human expertise remains irreplaceable in medical decision-making.

Oncology Research and TreatmentVol. 48(6)
German Cancer Research Center (DE), Heidelberg University (DE), Ludwigshafen University of Business and Society (DE), University Hospital Heidelberg (DE), Ministry of Education (ET), University Medical Centre Mannheim (DE)
Peace, Justice and strong institutions
Openalex Percentile: Top 7%
Sarcoma Diagnosis and Treatment
4.56
DOISourceOpenAlex
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Improving Accuracy and Source Transparency in Responses to Soft Tissue Sarcoma Queries Using GPT-4o Enhanced with German Evidence-Based Guidelines — Franka Menge, Cui Yang, et al. · Oncology Research and Treatment (2025) | TGRS Research Map | TGRS