Overexpression of Circ-Astn1 Suppresses Hyperglycemia-Induced Endothelial Cell Damage via the miR-138-5p/SIRT1 Axis
These findings suggest that circ-Astn1 promotes SIRT1 expression by sponging miR-138-5p. Circ-Astn1 overexpression suppresses HG-induced endothelial cell damage via miR-138-5p/SIRT1 axis.
Authors
- Hongbin Yu (ORCID: https://orcid.org/0000-0001-9511-9044)
- Dawei Liu (ORCID: https://orcid.org/0000-0003-4592-8358)
- Xueyan Wu (ORCID: https://orcid.org/0000-0001-9127-7854)
- Xiaoning Yan (ORCID: https://orcid.org/0000-0002-0829-0757)
- Siyang Liu
- Jianlong Wu
- Li-Yun Wang
Institutions
- Chengde Medical University (CN)
- Affiliated Hospital of Chengde Medical College (CN)
- Chengde Medical University (CN)
- Shanxi University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Current Medical Science
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1007/s11596-025-00011-9
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China