Prenatal Valproic Acid Exposure Impairs Offspring Cognition Through Disturbing Interneuron Development
Prenatal VPA exposure during the neurogenic period impaired the cognition of the offspring by disrupting interneuron migration and differentiation. The study provides a novel perspective on the influence of VPA over neurodevelopment.
Authors
- Yandong Zhang (ORCID: https://orcid.org/0009-0000-6170-5344)
- Yunli Xie (ORCID: https://orcid.org/0000-0002-7126-0972)
- Yunyun Huang (ORCID: https://orcid.org/0000-0001-7528-1001)
- Jing Ding (ORCID: https://orcid.org/0000-0001-5135-4210)
- Xin Wang (ORCID: https://orcid.org/0000-0003-2602-3967)
- Kaiyuan Shen
Institutions
- Sun Yat-sen University (CN)
- Fudan University (CN)
- Zhongshan Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- State Key Laboratory of Medical Neurobiology
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1111/cns.70303
- Primary Topic
- Pharmacological Effects and Toxicity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Key Research and Development Program of China