Thiol isomerase ERp18 enhances platelet activation and arterial thrombosis
ERp18 participates in platelet activation and thrombosis. Its function is, at least in part, through the regulation of integrin α<sub>IIb</sub>β<sub>3</sub> function. This finding expands our understanding of the role of thiol isomerases in the redox regulation of thrombosis and platelet function.
Authors
- Yue Han (ORCID: https://orcid.org/0009-0005-0791-3253)
- Zhenzhen Zhao (ORCID: https://orcid.org/0000-0002-6381-711X)
- Yi Lu
- Yi Wu (ORCID: https://orcid.org/0000-0002-5116-9266)
- Aizhen Yang
- Chao Fang
- Keyu Lv (ORCID: https://orcid.org/0000-0001-6097-4593)
- Jingyu Zhang (ORCID: https://orcid.org/0000-0003-4476-4304)
- Yuxin Zhang (ORCID: https://orcid.org/0009-0003-4006-5992)
- Miao Jiang (ORCID: https://orcid.org/0000-0002-3681-9494)
- Chao He (ORCID: https://orcid.org/0000-0001-5447-3098)
- Depei Wu (ORCID: https://orcid.org/0000-0002-0050-9830)
Institutions
- Hebei Medical University (CN)
- Soochow University (CN)
- Bioscience (China) (CN)
- Second Hospital of Hebei Medical University (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1016/j.rpth.2025.102706
- Citations
- 2
- Primary Topic
- Diet, Metabolism, and Disease
- Type
- article
- Field-Weighted Citation Impact
- 2.59
Funders
- National Natural Science Foundation of China
- Priority Academic Program Development of Jiangsu Higher Education Institutions
- State Key Laboratory of Radiation Medicine and Protection