Pectin-Zein-IPA nanoparticles promote functional recovery and alleviate neuroinflammation after spinal cord injury
Our findings provide a strategy for oral drug research in SCI. The results suggest that Pectin-Zein-IPA NPs have potential advantages for treatment and management of SCI. Reducing L-methionine intake may help reduce neuroinflammation after SCI.
Authors
- Siwang Hu (ORCID: https://orcid.org/0000-0002-8685-1441)
- Beini Wang (ORCID: https://orcid.org/0000-0002-2031-0327)
- Kailiang Zhou (ORCID: https://orcid.org/0000-0001-7795-576X)
- Yueqi Wu (ORCID: https://orcid.org/0000-0002-8958-1467)
- Abdullah Al Mamun (ORCID: https://orcid.org/0000-0002-7363-5934)
- Xianghang Chen (ORCID: https://orcid.org/0009-0009-7925-2094)
- Yang Lu (ORCID: https://orcid.org/0000-0002-2855-9637)
- Xinyuan Chen (ORCID: https://orcid.org/0000-0002-3241-6719)
- Jian Xiao (ORCID: https://orcid.org/0000-0001-7374-6506)
- Kui Du (ORCID: https://orcid.org/0000-0001-6698-3538)
- Shengfu Wang (ORCID: https://orcid.org/0000-0001-7175-4908)
- Shuangshuang Wang (ORCID: https://orcid.org/0000-0003-1634-5399)
- Anyu Du
- Qianqian Hu (ORCID: https://orcid.org/0000-0003-0310-0296)
- Chang Jiang
- Jiaqin Shao
Institutions
- Wenzhou Medical University (CN)
- Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University (CN)
- Zhejiang Lab (CN)
- The First People's Hospital of Wenling (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1186/s12951-025-03224-1
- Citations
- 2
- Primary Topic
- Spinal Cord Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 2.94
Funders
- National Natural Science Foundation of China