Pharmacological assessment of the anti-asthmatic potential of ethanolic extract from alpinia calcarata rhizome

Alpinia calcarata, commonly known as Dwarf Cardamom or Snap Ginger, is a perennial herb in the Zingiberaceae family. Various doses of the extract be administer including a dose of 2000 mg/kg and from which the low doses of 100 mg/kg and high dose was 200 mg/kg. At the high dose, no fatalities or adverse health effects were observed, indicating that the extract is well-tolerated. The positive safety profile at this dosage supports the selection of lower doses for further therapeutic evaluation. These findings suggest that the ethanolic extract possesses a favorable safety margin, positioning it as a promising candidate for subsequent pharmacological studies.