Clinical and molecular characteristics of periampullary carcinoma based on pathological subtypes
Pathologic typing-guided individualized chemotherapy resulted in prolonged survival for patients with advanced PAC. The PB and IN subtypes of PAC exhibit distinct molecular regulatory mechanisms and immune infiltration microenvironments. These findings underscore the importance of considering subtype-specific factors in the development of a PAC-PB diagnostic model.
Authors
- Xiang-Xu Wang (ORCID: https://orcid.org/0000-0002-1658-953X)
- Zhenghua Shi
- Qianrong Wang (ORCID: https://orcid.org/0000-0001-7555-812X)
- Hongmei Zhang (ORCID: https://orcid.org/0000-0002-4068-7017)
- Jingyue Yang (ORCID: https://orcid.org/0000-0001-6710-4937)
- Yue Yang (ORCID: https://orcid.org/0000-0001-5425-8216)
- Liping Ai
Institutions
- Xijing Hospital (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Journal of Gastrointestinal Oncology
- Published
- 2025-02-01
- DOI
- https://doi.org/10.21037/jgo-2025-14
- Primary Topic
- Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00