Expression of Claudin18.2 in metastatic lesions in peritoneum of gastric cancer

Although CLDN18.2 expression in PM mirrored that in primary lesions, the levels were generally reduced. When zolbetuximab is used for GC patients with peritoneal involvement, it is preferable to assess the expression of CLDN18.2 in the disseminated lesions.

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Publication Details

Journal
Journal of Gastrointestinal Oncology
Published
2025-02-01
DOI
https://doi.org/10.21037/jgo-24-743
Citations
4
Primary Topic
Barrier Structure and Function Studies
Type
article
Field-Weighted Citation Impact
3.37
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article

Expression of Claudin18.2 in metastatic lesions in peritoneum of gastric cancer

Joji Kitayama, Shin Saito, Kentaro Kurashina, Hideyo Miyato et al.
4 citations
Journal of Gastrointestinal Oncology
Barrier Structure and Function Studies
3.37
article

Expression of Claudin18.2 in metastatic lesions in peritoneum of gastric cancer

Joji Kitayama, Shin Saito, Kentaro Kurashina, Hideyo Miyato, Naohiro Sata, Hideyuki Ohzawa, Shiro Matsumoto, Hironori Yamaguchi, Rie Kawashima, Akira Saito, Yoshinori Hosoya
article en
4 citations

Abstract

Although CLDN18.2 expression in PM mirrored that in primary lesions, the levels were generally reduced. When zolbetuximab is used for GC patients with peritoneal involvement, it is preferable to assess the expression of CLDN18.2 in the disseminated lesions.

Journal of Gastrointestinal OncologyVol. 16(1)
Jichi Medical University (JP)
Good health and well-being
Openalex Percentile: Top 9%
Barrier Structure and Function Studies
3.37
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