Autoregulatory-guided management in traumatic brain injury: does age matter?
PRx was found to be an independent outcome predictor and influenced the safe and dangerous CPP and ΔCPPopt interval for all age groups. Thus, TBI patients older than 60 years may also benefit from autoregulatory-guided management and should not necessarily be excluded from future trials on such therapeutic strategies.
Authors
- Erta Beqiri (ORCID: https://orcid.org/0000-0002-8108-0000)
- Anders Hånell (ORCID: https://orcid.org/0000-0001-9369-3886)
- Teodor Svedung Wettervik (ORCID: https://orcid.org/0000-0002-4556-5721)
- Xuhang Chen (ORCID: https://orcid.org/0000-0001-6000-3914)
- Ihsane Olakorede (ORCID: https://orcid.org/0009-0009-8283-305X)
- Peter J. Hutchinson (ORCID: https://orcid.org/0000-0002-2796-1835)
- Andrea Lavinio (ORCID: https://orcid.org/0000-0002-8832-918X)
- Stefan Yu Bögli (ORCID: https://orcid.org/0000-0001-5386-0811)
- Adel Helmy (ORCID: https://orcid.org/0000-0002-0531-0556)
- Peter Smielewski (ORCID: https://orcid.org/0000-0001-5096-3938)
Institutions
- Uppsala University (SE)
- University of Cambridge (GB)
- Addenbrooke's Hospital (GB)
Publication Details
- Journal
- Acta Neurochirurgica
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1007/s00701-025-06474-y
- Citations
- 5
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 6.95
Funders
- National Science Foundation
- National Institute for Health and Care Research
- Royal College of Surgeons of England
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Uppsala Universitet
- Medical Research Council