Acute subanesthetic ketamine-induced effects on the mismatch negativity and their relationship to early and sustained treatment response in major depressive disorder

Acute NMDARs blockade reduced frontal MMN, with larger MMN reductions predicting greater symptom improvement. The MMN may serve as a non-invasive biomarker predicting antidepressant response to glutamatergic agents.

Authors

Pierre Blier (ORCID: https://orcid.org/0000-0003-1881-2421)
Verner Knott (ORCID: https://orcid.org/0000-0002-4969-3819)
Jennifer Lynne Phillips (ORCID: https://orcid.org/0000-0001-9635-8602)
Sara de la Salle (ORCID: https://orcid.org/0000-0002-1698-5938)

Institutions

University of Ottawa (CA)
Royal Ottawa Mental Health Centre (CA)

Publication Details

Journal: Journal of Psychopharmacology
Published: 2025-02-26
DOI: https://doi.org/10.1177/02698811251319456
Citations: 2
Primary Topic: Neuroscience and Music Perception
Type: article
Field-Weighted Citation Impact: 2.86

Funders

Canadian Institutes of Health Research

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article

Acute subanesthetic ketamine-induced effects on the mismatch negativity and their relationship to early and sustained treatment response in major depressive disorder

Pierre Blier, Verner Knott, Jennifer Lynne Phillips, Sara de la Salle

Feb 26, 2025

2 citations

Journal of Psychopharmacology

Neuroscience and Music Perception

2.86

article

Acute subanesthetic ketamine-induced effects on the mismatch negativity and their relationship to early and sustained treatment response in major depressive disorder

Pierre Blier, Verner Knott, Jennifer Lynne Phillips, Sara de la Salle

February 26, 2025article en

2 citations

Abstract

Acute NMDARs blockade reduced frontal MMN, with larger MMN reductions predicting greater symptom improvement. The MMN may serve as a non-invasive biomarker predicting antidepressant response to glutamatergic agents.

Journal of PsychopharmacologyVol. 39(6)

University of Ottawa (CA), Royal Ottawa Mental Health Centre (CA)

Canadian Institutes of Health Research

Good health and well-being

Openalex Percentile: Top 12%

Neuroscience and Music Perception

2.86

DOI Open Access PDF OpenAlex

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Acute subanesthetic ketamine-induced effects on the mismatch negativity and their relationship to early and sustained treatment response in major depressive disorder — Pierre Blier, Verner Knott, et al. · Journal of Psychopharmacology (2025) | TGRS Research Map | TGRS