Causal associations of inflammatory cytokines and urinary stones: a two-sample Mendelian randomization study
Our findings suggest a causal and unidirectional relationship between interleukin-18, stem cell growth factors, and USD. This indicates that these cytokines may actively contribute to the development or prevention of USD, offering a new avenue for clinical intervention based on cytokines modulation.
Authors
- Dan Yu (ORCID: https://orcid.org/0000-0002-3112-2292)
- Qingyun He (ORCID: https://orcid.org/0000-0003-3681-3751)
- Huan Yao (ORCID: https://orcid.org/0000-0001-5076-2650)
- Xu Ning
Institutions
- Sun Yat-sen University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- Translational Andrology and Urology
- Published
- 2025-02-01
- DOI
- https://doi.org/10.21037/tau-24-445
- Citations
- 2
- Primary Topic
- Digestive system and related health
- Type
- article
- Field-Weighted Citation Impact
- 3.63