ADH1B Gene Promotes Gastric Cancer Tumorigenesis and its Cisplatin Resistance through the EMT Pathway

This study identified the gene ADH1B as a critical factor in the incidence and drug resistance of gastric cancer. It was demonstrated through cellular and tumorigenic assays that ADH1B promotes carcinogenesis and enhances cisplatin resistance in gastric cancer cells via the EMT signaling pathways.

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Publication Details

Journal
Current Cancer Drug Targets
Published
2025-02-26
DOI
https://doi.org/10.2174/0115680096351094241125111654
Primary Topic
Cancer-related gene regulation
Type
article
Field-Weighted Citation Impact
0.00
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article

ADH1B Gene Promotes Gastric Cancer Tumorigenesis and its Cisplatin Resistance through the EMT Pathway

Zhenguo Pan, Chengcheng Gao
Current Cancer Drug Targets
Cancer-related gene regulation
article

ADH1B Gene Promotes Gastric Cancer Tumorigenesis and its Cisplatin Resistance through the EMT Pathway

Zhenguo Pan, Chengcheng Gao
article en

Abstract

This study identified the gene ADH1B as a critical factor in the incidence and drug resistance of gastric cancer. It was demonstrated through cellular and tumorigenic assays that ADH1B promotes carcinogenesis and enhances cisplatin resistance in gastric cancer cells via the EMT signaling pathways.

Current Cancer Drug TargetsVol. 25
Huaian First People’s Hospital (CN), Nanjing Medical University (CN)
Good health and well-being
Openalex Percentile: Top 97%
Cancer-related gene regulation
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ADH1B Gene Promotes Gastric Cancer Tumorigenesis and its Cisplatin Resistance through the EMT Pathway — Zhenguo Pan, Chengcheng Gao · Current Cancer Drug Targets (2025) | TGRS Research Map | TGRS