A Study of Some Physiological Variables in Women Suffering from Polycystic Ovary Syndrome in Diyala Governorate-Iraq

Polycystic ovary syndrome is an endocrine, metabolic, and polygenic genetic disorder that leads to infertility in about 10% of women of reproductive age. The current study aims to assess the impact of prolactin, progesterone, LH, TSH, FSH, insulin, and vitamin D3 on the risk of polycystic ovarian syndrome in women living in the Diyala population. In the current study, 33 samples from healthy women were used for the control group; the 54 samples were obtained from women patients with polycystic ovarian syndrome in the age range of 20 to 40 who returned to Al-Batoul Teaching Hospital and Al-Shams Laboratories in the center of Diyala Governorate. The samples were collected beginning in October 2022 and till May 2023 for the group of patients and healthy women’s. The current study's findings indicate that the levels of LH and testosterone in female patients varied significantly (P<0.05) in comparison to healthy women (7.78±3.62 Vs 5.43±2.81 and 0.52±0.21 VS 0.17±0.09). Conversely, it was shown that female patients' levels of vitamin D3 (24.31±11.85) were lower than those of healthy females (35.66±15.64). Lastly, there were no statistically significant changes (P > 0.05) found between the female patients and the healthy female patients in the levels of FSH, TSH, prolactin, and insulin. In addition to the existence of additional positive and negative correlations between the current variables, which are not significant, the study's results demonstrated a significant positive correlation between testosterone and FSH (P = 0.026, R = 0.304*) based on the Pearson correlation coefficient.