CHLAMYDIA OF VARIOUS ETIOLOGIES ON THE TERRITORY OF UKRAINE

Comprehensive microbiological and ecological-epidemiological studies carried out in Ukraine on significant field and clinical material made it possible to establish a wide range of zoonotic and anthroponotic chlamydia with their respective “epidemiological groups”. The circulation of chlamydia C. psittaci, C. trachomatis, C. pneumoniae was revealed and their etiological role was identified in a wide range of pathologies in birds, animals and people. The specific diagnosis of various forms of chlamydia based on the test has been improved: “The method of seeing C. trachomatis” (а.с. No.1723129), “The method of using a drug for the diagnosis of chlamydial infection” (patent 59959 A, Ukraine), immunoenzyme test system (approved laboratory regulations). The specificity of daily diagnostic tests (culture, PСR, DIF, IIFR, EIA) for the detection of chlamydia of various etiologies and localization has been determined. 9 strains of C. trachomatis were isolated from men, women with urogenital infections and children with respiratory pathology using the disaggregated method (a.c. No. 1723129), which has a lower expression virulent, antigenic, allergenic power, lower standard strain “B” and author’s strain “K” of C. psittaci. In modern Ukraine, a high level of infection with C. psittaci has been established in 83 species of wild birds (up to 75%). The circulation of strains of C. psittaci with varying virulence was revealed, which includes both latent passage of ornithosis and epizootics and epidemics, and in some cases lethal infection in humans. Epizootic cases of psittacosis have been established on the island Kruglyy and Kuyalnik estuary with the registration of significant epizootics in new species of wild birds — eiders, sandpipers, which confirms the persistence, polygonal nature of the natural environment of ornithosis in the Black Sea biosphere reserve. First, a high infection rate of C. psittaci in wild leaves of 18 species (up to 40%) was revealed, which contributes to the reservoir of chlamydial infection in nature. A high infectivity rate of C. psittaci great horned thinness was established from the detection of epizootic animals and those caught before the epidemic by a professional contingent of agricultural firms, which confirmed the presence of an anthropourgic infection. Polyinfectious natural diseases have been identified, which will require a polynosological approach to their monitoring, covering the area of widespread mixed-infected noses and carriers. A wide variety of urogenital and extragenital forms of chlamydia, caused by C. trachomatis, have been recorded in women, people with various infections of the urogenital system and children with respiratory pathology. An algorithm for diagnosing chlamydia with different stages of the infectious process (hospital, chronic, persistent) has been developed. High productivity of complex treatment of patients with various pathologies of the urogenital tract, organs of the eye and joints has been achieved. Native strains of chlamydia have been identified with the establishment of an epidemiological “father-child” relationship, which will require the inclusion of children in the “epidemiological group”. A set of scientifically based recommendations has been developed to improve the system of prevention of zoonotic and anthroponotic chlamydia in Ukraine, which will accommodate improved biosafety of the population.