A Novel Digital PCR Assay for Accurate Detection and Differentiation of Focal and Non-Focal Subtypes of Mesenchymal–Epithelial Transition (MET) Gene Amplification in Lung Cancer
This study highlights the potential of the dPCR assay to complement existing molecular diagnostic techniques, delivering reliable and actionable results for <i>MET</i>-targeted therapy selection in NSCLC patients and thereby advancing precision oncology.
Authors
- Jimmy Yiu-Wing Lam (ORCID: https://orcid.org/0000-0001-5245-8716)
- Victor Tang (ORCID: https://orcid.org/0000-0003-2792-0248)
- G. G. Siu (ORCID: https://orcid.org/0000-0002-4354-3393)
- Rebecca S.Y. Wong (ORCID: https://orcid.org/0000-0002-0911-718X)
- Ling Ning Lam
- Joshua Hoi-Yan Ng (ORCID: https://orcid.org/0000-0002-6909-8662)
- Peggy S. N. Li
- F Hioe
- S. Leung
- Y.H. Lui
- Huang Chu
- Miranda Chong-Yee Yau
- Raymond C. M. Shek
Institutions
- Hospital Authority (HK)
- Hong Kong Polytechnic University (HK)
- Pamela Youde Nethersole Eastern Hospital (CN)
Publication Details
- Journal
- Cancers
- Published
- 2025-02-26
- DOI
- https://doi.org/10.3390/cancers17050811
- Citations
- 2
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.61