Electroacupuncture Improves Learning and Memory Impairment in Rats with Cerebral Ischemia/Reperfusion Injury by Promoting Microglia/Macrophage M2 Polarization Through Nrf2/HO-1 Pathway
EA effectively improved learning and memory impairments in MCAO rats by activating the Nrf2/HO-1 signaling pathway, leading to the promotion of M2 polarization in microglia/macrophages.
Authors
- Jun Wan (ORCID: https://orcid.org/0000-0003-4865-783X)
- Xiaofei Wang (ORCID: https://orcid.org/0000-0002-8647-5271)
- Wenjing Li (ORCID: https://orcid.org/0000-0003-1154-2895)
- Shuying Chen (ORCID: https://orcid.org/0009-0000-8596-0630)
- Limin Chen (ORCID: https://orcid.org/0000-0001-5228-3522)
- Kexin Sun (ORCID: https://orcid.org/0009-0008-8267-8195)
- Yanjie Bai
- Yuqian Xiao
- An Liu
Institutions
- First Affiliated Hospital of Henan University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/jir.s504670
- Citations
- 7
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 5.90