Finerenone Ameliorates High Glucose-Induced Podocytes Epithelial-Mesenchymal Transition Through the Regulation of Krüppel-Like Factor 5 in Diabetic Nephropathy
Our results suggest that finerenone could alleviate high glucose-induced podocyte EMT via regulating KLF5. Further investigation is warranted to elucidate the precise underlying mechanism.
Authors
- Qinglian Wang (ORCID: https://orcid.org/0000-0002-1622-1815)
- Jingshu Sun (ORCID: https://orcid.org/0000-0002-2085-6653)
- Simeng Wang (ORCID: https://orcid.org/0000-0001-9708-8851)
- Jianqiang Shu (ORCID: https://orcid.org/0000-0002-7309-9967)
- Nannan Chong
- Xinyu Zhang (ORCID: https://orcid.org/0009-0008-0290-7374)
- Dandan Chen
- Zhikang Sun
- Ying Xu (ORCID: https://orcid.org/0000-0002-6340-3662)
- Wenzhen Chen (ORCID: https://orcid.org/0009-0002-0242-9508)
Institutions
- Second Hospital of Shandong University (CN)
- Weifang People's Hospital (CN)
- Shandong Provincial Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Diabetes Metabolic Syndrome and Obesity
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/dmso.s503133
- Citations
- 1
- Primary Topic
- Kruppel-like factors research
- Type
- article
- Field-Weighted Citation Impact
- 0.81