<i>Free and Easy Wanderer</i> Ameliorates Intestinal Bloating‐Dependent Avoidance Behavior of <i>Caenorhabditis elegans</i> Through Gut‐Germline‐Neural Signaling
FAEW protects against avoidance behavior of C. elegans through downregulating H4K8ac protein expression and activating DAF-16. This study provides crucial experimental evidence supporting FAEW as a promising candidate for protecting against avoidance behavior associated with PTSD.
Authors
- Yingying Xu
- Ping Qiu (ORCID: https://orcid.org/0000-0003-3497-907X)
- Hanxiao Wang (ORCID: https://orcid.org/0000-0002-9809-8119)
- Siyi Lin (ORCID: https://orcid.org/0000-0002-7968-653X)
- Senlin Shi (ORCID: https://orcid.org/0000-0003-3608-3496)
- Chunlan Hong (ORCID: https://orcid.org/0000-0002-8671-7138)
- Yu Zhao (ORCID: https://orcid.org/0000-0001-8179-4903)
- Changyu Li (ORCID: https://orcid.org/0000-0001-8656-0428)
- Thomas Efferth (ORCID: https://orcid.org/0000-0002-3096-3292)
- Jiale Wei (ORCID: https://orcid.org/0009-0008-3274-4668)
- Haoyue Fu
- Sheng Du (ORCID: https://orcid.org/0000-0002-5580-399X)
Institutions
- Zhejiang Chinese Medical University (CN)
- Johannes Gutenberg University Mainz (DE)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1111/cns.70291
- Primary Topic
- Genetics, Aging, and Longevity in Model Organisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Zhejiang Chinese Medical University