Copper‐Catalyzed 1,5‐Trifluoromethyl‐thio(seleno)cyanation of 5‐Hexenenitriles with an Intramolecular Cyano Migration
A copper-catalyzed remote 1,5-trifluoromethyl thio(seleno)cyanation of 5-hexenenitriles with an intramolecular cyano migration has been established, affording a variety of CF<sub>3</sub>/CN-containing thiocyanates and selenocyanates under mild conditions. The reaction features high chemo- and regioselectivities and illustrates potential value in synthetic chemistry.
Authors
- Zhixian Wang (ORCID: https://orcid.org/0000-0002-0515-8312)
- Jiaqi Wang (ORCID: https://orcid.org/0000-0002-8616-3200)
- Yining Sun
- Kang Guo
Institutions
- Hebei Normal University (CN)
Publication Details
- Journal
- Chemistry - An Asian Journal
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1002/asia.202500241
- Citations
- 1
- Primary Topic
- Fluorine in Organic Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.79