Fluvastatin Promotes Treg Cell Production in Allogeneic Immune Reaction and Suppresses Inflammatory Response
Our finding demonstrated that statin exposure modulates immune responses during the initial phase of allo-HSCT by promoting Treg expansion and suppressing inflammatory reactions, which supply a promising strategy for aGVHD prevention.
Authors
- Donghai Tang
- Xianxian Chen
- Li Zhao (ORCID: https://orcid.org/0000-0001-5600-5087)
- Kailin Xu (ORCID: https://orcid.org/0000-0003-1375-1084)
- Chunxiao Ren
- Fen Yan
- Yu Tian (ORCID: https://orcid.org/0000-0002-5997-1456)
- Kai Zhao (ORCID: https://orcid.org/0000-0003-1740-3239)
- Dong Huang
Institutions
- Xuzhou Medical College (CN)
Publication Details
- Journal
- Immunity Inflammation and Disease
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1002/iid3.70165
- Citations
- 2
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 1.59
Funders
- Government of Jiangsu Province
- Xuzhou Medical University