Photocatalytic Reduction of Allyl Sulfones to Sulfides via Phosphine‐Mediated Deoxygenation
PPh<sub>3</sub> is shown to be an effective reagent for the deoxygenative reduction of allyl sulfones to sulfides under photocatalytic conditions. Cross-over experiment suggests that the reaction proceeds in a sequential approach involving radical fragmentation and deoxygenation of sulfonyl radical to a thiyl radical, which recombines with the terminal alkene. This mild protocol exhibits broad functional group tolerance, and its applications are explored through scale-up reactions.
Authors
- Jiannan Zhao (ORCID: https://orcid.org/0000-0002-5546-7383)
- Wen-Deng Liu
- Jia‐Nan Mo
- Wencheng Han (ORCID: https://orcid.org/0000-0002-1452-9832)
- Wentao Wang (ORCID: https://orcid.org/0000-0002-3876-8627)
Institutions
- Dalian Institute of Chemical Physics (CN)
- Chinese Academy of Sciences (CN)
- Dalian University of Technology (CN)
Publication Details
- Journal
- Chemistry - An Asian Journal
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1002/asia.202401807
- Citations
- 2
- Primary Topic
- Chemical Synthesis and Reactions
- Type
- article
- Field-Weighted Citation Impact
- 1.87