Effect of Metformin on Spermatogenesis Restoration Following Spermatogonial Stem Cell Transplantation in An Azoospermia Mouse Model.
Transplantation of SSCs combined with metformin significantly enhances spermatogenesis and improves the homing efficiency of transplanted SSCs. This approach holds great potential for restoring fertility in clinical settings, particularly in childhood cancer survivors.
Authors
- Shokoofeh Kazemzadeh (ORCID: https://orcid.org/0000-0002-0068-5770)
- Azim Hedayatpour
- Peyman Modarresi
- Alieh Bashghareh
Institutions
- Islamic Azad University Shabestar (IR)
- Islamic Azad University, Shoushtar Branch (IR)
Publication Details
- Journal
- PubMed
- Published
- 2025-02-23
- DOI
- https://doi.org/10.22074/cellj.2025.2040810.1669
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 0.00