Computer-Aided Decision Support and 3D Models in Pancreatic Cancer Surgery: A Pilot Study
<b>Background:</b> Preoperative planning of patients diagnosed with pancreatic head cancer is difficult and requires specific expertise. This pilot study assesses the added value of three-dimensional (3D) patient models and computer-aided detection (CAD) algorithms in determining the resectability of pancreatic head tumors. <b>Methods:</b> This study included 14 hepatopancreatobiliary experts from eight hospitals. The participants assessed three radiologically resectable and three radiologically borderline resectable cases in a simulated setting via crossover design. Groups were divided in controls (using a CT scan), a 3D group (using a CT scan and 3D models), and a CAD group (using a CT scan, 3D and CAD). For the perceived fulfillment of preoperative needs, the quality and confidence of clinical decision-making were evaluated. <b>Results:</b> A higher perceived ability to determine degrees and the length of tumor-vessel contact was reported in the CAD group compared to controls (<i>p</i> = 0.022 and <i>p</i> = 0.003, respectively). Lower degrees of tumor-vessel contact were predicted for radiologically borderline resectable tumors in the CAD group compared to controls (<i>p</i> = 0.037). Higher confidence levels were observed in predicting the need for vascular resection in the 3D group compared to controls (<i>p</i> = 0.033) for all cases combined. <b>Conclusions:</b> "CAD (including 3D) improved experts' perceived ability to accurately assess vessel involvement and supports the development of evolving techniques that may enhance the diagnosis and treatment of pancreatic cancer".
Authors
- Igor Jacobs (ORCID: https://orcid.org/0000-0002-7820-3604)
- Marc G. Besselink (ORCID: https://orcid.org/0000-0003-2650-9350)
- J. Sven D. Mieog (ORCID: https://orcid.org/0000-0002-3649-8504)
- Bas Groot Koerkamp (ORCID: https://orcid.org/0000-0003-1917-6973)
- Alexander L. Vahrmeijer (ORCID: https://orcid.org/0000-0001-9370-0011)
- Mark Ramaekers (ORCID: https://orcid.org/0000-0003-2120-7230)
- Olivier R. Busch (ORCID: https://orcid.org/0000-0001-9605-6831)
- Wouter W. te Riele (ORCID: https://orcid.org/0000-0002-5256-3919)
- Ronald M. van Dam (ORCID: https://orcid.org/0000-0001-8415-5090)
- Joris I. Erdmann (ORCID: https://orcid.org/0000-0001-8233-1505)
- Bert A. Bonsing (ORCID: https://orcid.org/0000-0003-4513-5737)
- Misha D. P. Luyer (ORCID: https://orcid.org/0000-0002-9483-1520)
- Joost Nederend (ORCID: https://orcid.org/0000-0002-9905-5866)
- Luc Geurts (ORCID: https://orcid.org/0000-0002-9608-9147)
- Marcel den Dulk (ORCID: https://orcid.org/0000-0002-6161-161X)
- Jenny Dankelman (ORCID: https://orcid.org/0000-0003-3951-2129)
- Erwin van der Harst (ORCID: https://orcid.org/0000-0002-1317-5614)
- Diederik W. M. Rasenberg
- Ignace H. J. T. de Hingh (ORCID: https://orcid.org/0000-0003-3491-4268)
- Jon R. Pluyter
- Rinze Reinhard
- Freek D. Daams (ORCID: https://orcid.org/0000-0001-6323-6342)
- Bin Yu (ORCID: https://orcid.org/0000-0002-1862-5936)
- Frank Willem Jansen (ORCID: https://orcid.org/0000-0002-6192-3787)
- John C. P. van der Ven
Institutions
- NXP (Netherlands) (NL)
- Radboud University Nijmegen (NL)
- Leiden University Medical Center (NL)
- Maastricht University Medical Centre (NL)
- Catharina Ziekenhuis (NL)
- Maastricht University (NL)
- St. Antonius Ziekenhuis (NL)
- OLVG (NL)
- Maasstad Ziekenhuis (NL)
- Philips (Netherlands) (NL)
- Amsterdam University Medical Centers (NL)
- Eindhoven University of Technology (NL)
- Erasmus University Rotterdam (NL)
- Delft University of Technology (NL)
Publication Details
- Journal
- Journal of Clinical Medicine
- Published
- 2025-02-26
- DOI
- https://doi.org/10.3390/jcm14051567
- Citations
- 2
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 2.09