IBC Oxford University Oral Abstract 3 - Audit of outcome of SADIS- results from a single bariatric centre

Abstract Introduction Obesity is a growing concern globally. Surgical treatment of obesity includes Sleeve gastrectomy and Gastric bypass. These procedures can suffer inadequate weight loss and weight re-gain. SADIS- Single anastomosis Duodeno-ileal switch is a variant of Duodenal switch procedure that it gives good weight loss, weight maintenance and resolutions of obesity related morbidity. There has been concern about the nutritional deficiencies associated with SADIS and it is a technically challenging procedure, so it has limited the uptake. Methods It is a retrospective study with prospective data collection. We analyzed our results of all patients who underwent SADIS procedure from January 2016–December 2022. Primary aim-Weight loss and morbidity resolution at 6 months, 1 year, 2 years and 6–10 yearsNutritional deficiencies. Results 17 patients underwent SADIS procedure from January 2016–December 2022. Of these patients, majority are women. Age range between 27–62. Average BMI 55 kg/m2, BMI range 35 kg/m2–96.2 Kg/m2. Average weight loss was 32% (15%–53%) at 6 months, 69.6% (34%–90%) at 1 year and 86.2%. (Range 43%–109%) at 2 years, 6–10 years follow up is available for 16 out of 17 patients (One patient was lost to follow up). Average weight loss was 76% (62%–96%). None of the patients had protein energy malnutrition. 4 patients had Zinc and 3 had Calcium deficiency, all managed with oral replacement. Conclusions SADIS gives good outcomes in terms of weight loss and resolution of co-morbidities. Long term weight maintenance is better than bypass. Risk of nutritional deficiencies is acceptable and similar to bypass