A tumor-binding antibody with cross-reactivity to viral antigens
These findings suggest that memory B cells against a viral target could have affinity matured to produce an antibody that recognizes a similar epitope on tumor cells and exhibits antitumor properties.
Authors
- Elizabeth B. Gottlin (ORCID: https://orcid.org/0000-0003-0886-0024)
- Edward F. Patz (ORCID: https://orcid.org/0000-0003-3374-1596)
- Michael J. Campa (ORCID: https://orcid.org/0000-0003-4146-2706)
- Kevin Wiehe
Institutions
- Duke University (US)
Publication Details
- Journal
- Cancer Immunology Immunotherapy
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1007/s00262-025-03975-8
- Citations
- 6
- Primary Topic
- Monoclonal and Polyclonal Antibodies Research
- Type
- article
- Field-Weighted Citation Impact
- 8.16