Acute Seizure Activity During F-18 FDG PET/CT Imaging

We report a 62-year-old man with acute seizure during FDG PET/CT imaging. Initially admitted for newly diagnosed epilepsy, CT and MRI brain studies were unremarkable. Subsequent PET/CT showed focal tracer uptake in the left hippocampus with jerking of bilateral upper limbs and trunk. Delayed PET/CT supported the initial findings of transient seizure activity. This timely diagnosis allowed for rapid optimization of his anti-epileptic agents for the rest of the admission. This case illustrates a rare presentation of seizure during FDG PET/CT scanning and highlights the importance of distinguishing between motion artifacts and genuine seizure activity for timely diagnosis and management.