Genomic and micro-environmental insights into drug resistance in colorectal cancer liver metastases
This study reveals how genomic and TME-driven factors contribute to drug resistance in CRC liver metastases. Integrating these insights with clinical data could advance precision therapies, addressing the evolving challenge of tumor drug resistance in CRC.
Authors
- Siwei Zhou (ORCID: https://orcid.org/0009-0008-7390-0671)
- Yuan Xia (ORCID: https://orcid.org/0000-0002-7292-8903)
- Weizhen Huang (ORCID: https://orcid.org/0000-0002-8959-3839)
- Junjie Kuang (ORCID: https://orcid.org/0000-0001-8587-5065)
- Jinbo Lin
- Jun Li (ORCID: https://orcid.org/0000-0003-0572-1344)
- Yi Li (ORCID: https://orcid.org/0000-0002-6819-2462)
Institutions
- Huizhou Central People's Hospital (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-02-26
- DOI
- https://doi.org/10.1007/s12672-025-01976-8
- Primary Topic
- Colorectal Cancer Treatments and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Basic and Applied Basic Research Foundation of Guangdong Province