IBD-DISK AS A TOOL ESTIMATING THE PREVALENCE OF INFLAMMATORY BOWEL DISEASE-RELATED DISABILITY AND ASSOCIATED INFLUENCING FACTORS MOROCCO: A CROSS-SECTIONAL STUDY

Introduction: IBD can cause physical, psychological, family and social impairments. Quality of life of IBD patients is usually worse than general population. The aim of our study is to evaluate the quality of life of IBD patients in a Moroccan center, to determine its influencing factors and to calculate a cut-off for this score. Methods: This is a 6-month prospective study, both descriptive and analytic, conducted from November 2021 to April 2022, with patients followed on an out-patient basis or in consultation at our department. The IBD-Disk questionnaire was explained to the patients and completed by the same doctor. Results: 100 patients were included. Median age of our patients was 45 [28.3-56] with an equal number of male and female participants. 72 patients (72%) had Crohns disease for 28 patients followed for UC (28%). Median score of IBD-disk was 21.5 [9.25 - 42]. In univariate analysis, there is a statistically very significant difference in the total score of the IBD-Disk between sexes (p=0.006), therapeutic classes (0.018), use of an immunosuppressant (0.001), and clinical remission. In multivariate analysis, only immunosuppression emerges as a factor associated with the IBD-disk score. Finally, the value of 36 have been determined as a cut-off. A score 36 matched with a patient in clinical remission. Conclusion: Our study is the first in Morocco to use the IBD-Disk in assessing the quality of life of IBD patients. It showed that the disease significantly impacts the quality of life of our patients (mainly female and on immunosuppressants), both psychologically (energy and emotions) and sexually, whether they are being treated for CD or UC. A cut-off score of 36 was assessed and can be used in our daily practice as a score below which clinical remission could be defined.